Supports mitochondrial, cognitive and cardiovascular health, providing 24 hour sustained release MicroActive CoQ10 with BioPQQ. PQQ (pyrroloquinoline quinone) is a novel co-factor with antioxidant and B vitamin-like activity. It is naturally present in vegetables and in the human body, including breast milk, and posseses unique neuroprotectant and cardioprotectant properties. MicroActive CoQ10 is a water-soluble, submicron particle-sized CoQ10 generated using a patented process that complexes each CoQ10 molecule with a beta-cyclodextrin molecule. CoQ10 is bound to the lipophilic end of the molecule, while the other end is hydrophilic, facilitating dispersion and transport. At the cellular surface, the complex dissociates, liberating a single CoQ10 molecule for efficient absorption. The extended 24-hour release of MicroActive CoQ10 also allows for convenient, once-daily dosing.
Clinical research indicates superior absorption compared to solubilized and crystalline CoQ10, with low inter-subject variance. SR- CoQ10 with PQQ provides antioxidant and mitochondrial support through different mechanisms, providing multifunctional support for cardiovascular health. Research indicates that both PQQ and CoQ10 support heart muscle function and healthy cellular oxygen utilization. However, the mechanisms for this support differ. Studies suggest that PQQ promotes mitochondrial synthesis and function, while CoQ10 promotes energy production as a core component of cellular respiration. These actions are particularly supportive of tissues that require a lot of energy, such as the heart muscle. Furthermore, they acts as antioxidants, providing protection from free-radicals and helping to maintain the integrity of cellular membranes. Numerous studies have indicated that PQQ supports nerve health. Mechanistic investigations suggest that PQQ supports several signal transduction pathways that are important in maintaining mitochondrial homeostasis and oxidative metabolism. Like CoQ10, PQQ is a powerful antioxidant that supports mitochondrial function. PQQ also supports healthy levels of nerve growth factor and glutamate receptor activity. Several studies suggest that PQQ may promote learning ability and memory. In a double-blind, placebo controlled
clinical trial conducted in 71 middle-aged individuals, PQQ supplementation over a 12 week period supported healthy cognitive performance, and a combination of PQQ and CoQ10 provided greater support than PQQ alone. BioPQQ pyrroloquinoline quinone disodium salt is manufactured in Japan using a patented natural fermentation process. It contains 2.7 mg sodium per capsule. MicroActive CoQ10-cyclodextrin complex (SR-CoQ10) contains coenzyme Q10 obtained naturally from fermentation and potato starch.

Each Serving Contains	Amount per Serving	% of Daily Value
coenzyme Q10\t(from MicroActive\u00ae Q10-cyclodextrin complex)	100mg	*
BioPQQ\u2122 pyrroloquinoline quinone disodium salt\t	20mg	*
* Percent of Daily Value Not Established

Dairy-Free, Wheat-Free, Yeast-Free, Gluten-Free, Corn-Free, Sugar-Free, Soy-Free, No Hydrogenated Oils Or Preservatives